1. Cerebellar associative sensory learning defects in five mouse ...
9 jul 2015 · Adriana Cherskov. Department of Molecular Biology and Princeton Neuroscience Institute, Princeton University, Princeton, United States ...
On a windy day, hearing the sound of wind makes many individuals squint in anticipation in order to protect their eyes. Linking two sensations that arrive within a split second of one another, such as sound and the feeling of wind, is a type of learning that requires the cerebellum, a region found at the base of the brain. When done in a laboratory setting, this particular form of learning has been dubbed eyeblink conditioning. Individuals with autism tend to have difficulties with appropriate matching of different senses. For example, they have trouble identifying a video that goes with a spoken soundtrack. They also do not learn eyeblink conditioning the same way that other individuals do. However, it is not known which circuits in the brain are responsible for their difficulty. Kloth et al. now investigate this issue by asking whether versions of genes that increase the risk of autism in humans also disrupt eyeblink conditioning in mice. They tested five types of mouse model, each with a different genetic mutation that has previously been linked to autism. All five of these mutations cause defects in different cell types of the cerebellum, and all mice have abnormal social and habitual behaviors, similar to autistic people. The tests involved shining a bright light at the mice, which was followed, a split second later, by a puff of air that always causes the mice to blink. After this had occurred dozens of times, the mice started to blink earlier, as soon as the light appe...
2. Outcomes to PhDs Conferred < MD-PhD Program
Adriana Cherskov,“Cellular and molecular features of cerebellar evolution in primates” Mentor: Nenad Sestan, MD, PhD; Interdepartmental Neuroscience Program.
Adriana Cherskov,“Cellular and molecular features of cerebellar evolution in primates” Mentor: Nenad Sestan, MD, PhD; Interdepartmental Neuroscience Program
3. Schizophrenia-associated somatic copy-number variants from ... - NCBI
We show that ABCB11 is strongly expressed in human DA neurons, specifically within the dorsal stream of the SN. ... Frisbie, Adriana Cherskov, Liana Fasching ...
While germline copy-number variants (CNVs) contribute to schizophrenia (SCZ) risk, the contribution of somatic CNVs (sCNVs)—present in some but not all cells—remains unknown. We identified sCNVs using blood-derived genotype arrays from ...
4. [PDF] FOSTERING LEADERSHIP - Sustainability at Princeton
• Pilot a single-stream recycling program and compare it with the existing ... • Following the restoration of Washington Road stream ... and Adriana Cherskov '14. ( ...
5. [PDF] 20 May 2024 - Yale University
20 mei 2024 · Adriana Cherskov. Tyrone DeSpenza, Jr. Carrie ... Adriana Cherskov. BA ... The Role of Microglia in the Developing Rostral Migratory Stream.
6. [XLS] T120 - NRSA Individ Fellows - R1120.xls
... Cherskov, Adriana, 5, F30, NIMH, F30MH123074-03, 1, $52,694, YALE UNIVERSITY, YALE UNIVERSITY OFFICE OF SPONSORED PROJECTS, PO BOX 208327, NEW HAVEN ...
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7. Lhx6 Activity Is Required for the Normal Migration and Specification ...
21 mrt 2007 · ... Stream · Abstract · Fulltext · PDF · Neuronal Death Resulting from Targeted ... Miller, Adriana Cherskov, Mo Yang, Anahita Amiri, Gianfilippo ...
The cerebral cortex contains two main neuronal cell populations, the excitatory glutamatergic (pyramidal) neurons and the inhibitory interneurons, which synthesize GABA and constitute 20–30% of all cortical neurons. In contrast to the mostly hom*ogeneous population of projection neurons, cortical interneurons are characterized by remarkable morphological, molecular, and functional diversity. Among the markers that have been used to classify cortical interneurons are the calcium-binding proteins parvalbumin and calretinin and the neuropeptide somatostatin, which in rodents identify mostly nonoverlapping interneuron subpopulations. Pyramidal neurons are born during embryogenesis in the ventricular zone of the dorsal telencephalon, whereas cortical interneurons are generated in the subpallium and reach the cortex by tangential migration. On completion of tangential migration, cortical interneurons switch to a radial mode of migration and enter the cortical plate. Although the mechanisms that control the generation of interneuron diversity are currently unknown, it has been proposed that their site of origin in the ventral forebrain determines their specification into defined neurochemical subgroups. Here, we show that Lhx6 , a gene induced in the medial ganglionic eminence and maintained in parvalbumin- and somatostatin-positive interneurons, is required for the specification of these neuronal subtypes in the neocortex and the hippocampus. We also show that Lhx6 activity is requi...
8. Takumi Toru (00222092) - KAKEN — Researchers
... stream to study autonomic nervous and neuroendocrine system ... stream to study autonomic nervous and neuroendocrine system ... Adriana Cherskov, Taisuke Miyazaki, ...
Affiliation (Current)：神戸大学,医学研究科,教授, Research Field：Biological Sciences,Biological Sciences,Basic / Social brain science,Pathological medical chemistry,Pathological medical chemistry, Keywords：神経科学,遺伝子,自閉症,生理学,脳・神経,行動学,時計遺伝子,脳神経疾患,クローニング,概日リズム, # of Research Projects：69, # of Research Products：591, Ongoing Project：自閉症における社会性回路遷移機構の解明
9. Hokkaido University - Masahiko WATANABE - 北海道大学研究者総覧
... stream is well known, but the endocrine hormonal ... stream, and the expression of the essential NR1 subunit ... Adriana Cherskov, Taisuke Miyazaki, Masahiko ...
Enhancement of Haloperidol-Induced Catalepsy by GPR143, an L-Dopa Receptor, in Striatal Cholinergic Interneurons.
10. [PDF] The Pattern Seekers
Bullmore, Bhismadev Chakrabarti, Tony Charman, Emma Chapman, Adriana. Cherskov ... “Segmentation of the speech stream in a non-human primate: Statistical.
11. Arro_Corporation__ilnbke-19-35238 ... - PacerMonitor
... Stream, IL 60132-0500 Adriana Perez Advanced ... Stream, IL 60132-0500 Adriana Perez Advanced Packaging ... Cherskov & Flaynik 300 N. State Street, Suite 510 ...
12. [PDF] PART 1 - USPTO
Cherskov, Michael J. Childress, George Herman ... Carol Stream, Ill. 60188. Doylestown, Pa 1890 I ... Adriana S. Dallas, Tex. 75240. North Canton, Ohio ...
13. [DOC] 2010 Candidates for the Presidential Scholars Program
IL - Carol Stream - Alejandro A. Argueta, Benet Academy. IL - Carol Stream - Nicholas J. ... WA - Redmond - Adriana Cherskov, Unknown High School. WA - Redmond - ...
14. 渡辺 雅彦(ワタナベ マサヒコ)(医学研究院 生理系部門 解剖学分野)
... stream, and the expression of the essential NR1 ... stream odour discrimination. Olfactory memory ... Simmons, Tahra Eissa, Jin Nakatani, Adriana Cherskov ...
Enhancement of Haloperidol-Induced Catalepsy by GPR143, an L-Dopa Receptor, in Striatal Cholinergic Interneurons.
15. a13 control mouse: Topics by Science.gov
... Cherskov, Adriana; Miyazaki, Taisuke; Watanabe ... twitch muscles to overload. Males of eight ... Seelye, Adriana; Hagler, Stuart; Mattek, Nora; Howieson ...
16. [PDF] 2013-2014 - Princeton University Art Museum
30 mei 2014 · The need to develop a sustainable stream of operating funds and make the case for future ... Adriana Cherskov. Jin Yun Chow. Andrea Chu. Suhryoung ...
17. skills deficit model: Topics by WorldWideScience.org
... Cherskov, Adriana; Miyazaki, Taisuke; Watanabe ... stream velocity, which is computed based on measured flow rates during the experiments. ... stream processing.
18. ABRAMOVIC, JOHN Basketball-Military-Business
They have three children: Adriana, Ivana, and Stephan. ... As the bride of Benedikt Cherskov, she traveled ... stream from our two placer claims. There had been a ...
19. Full text of "Memphis State University Faculty-Staff-Student Telephone ...
... CHERSKOV GUY JOHN CHESTER JAMES ALAN CHESTER JAMES EDWARD CHESTER LINDA ANN ... ADRIANA MARIA DE ZONIA MICHAEL LEON DEADERICK LADY CAMILLE DEAKINS JAMES ...
